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| Product Name: |
BMY 30120
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| Specifications |
Chlorhexidine phosphanilate |
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| Topical chlorhexidine diphosphanilate (WP-973) in burn wound sepsis. McManus, Albert T.; Denton, Camille L.; Mason, Arthur D., Jr. (US Army Inst. Surg. Res., Fort Sam Houton, TX 78234, USA). Arch. Surg. (Chicago), 119(2), 206-11 (English) 1984. CODEN: ARSUAX. ISSN: 0004-0010. ***UMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 10 WP-973 (I) [77146-42-0], as a 2% cream, was studied for its therapeutic activity in 2 rat models of fatal burn wound infection. Control treatments were infection and placebo cream; infection only; infection and 1% sulfadizine silver; and burning only. Also are selling on guidechem. Activity against Pseudomonas aeruginosa or Proteus mirabillis was tested in surface-inoculated rats with 20% scalds. Treatment were initiated 24 h or 4 h, resp., after inoculation. 77146-42-0 is also in the experiment. Pseudomonas-Infected rats were treated once a day for 10 days. Proteus-Infected rats were treated once a day for 5 days. In these exptl. models, chlorhexidine diphosphanilate was equal to silver sulfadiazine, an established topical chemotherapeutic agent. In vitro activity was examd. using bacteremia isolated from 65 burned patients. Using agar diffusion trench plates, chlorhexidine diphosphanilate was active against all strains. No evidence of cross-resistance between sulfonamide and chlorhexidine diphosphanilate its components was obsd. |
| Company: |
Xiamen Wu Hua Chemical Co., Ltd
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| Contact: |
Ms. Freya Han |
| Address: |
Sports Road 321,Xiamen City, Fujian Province, China |
| Postcode: |
361000 |
| Tel: |
86-0592-84563215 |
| Fax: |
86-0592-84563215 |
| E-mail: |
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